DOI: 10.12890/2016_000502

Toxic Epidermal Necrolyisis and Sepsis

Authors

  • Daniela Dias Alves Internal Medicine Department Hospital Amato Lusitano, Castelo Branco
  • Nulita Lourenço Intensive Care Department, Hospital Amato Lusitano, Castelo Branco
  • Daniela Franco Internal Medicine Department, Hospital Amato Lusitano, Castelo Branco
  • Eufémio Calmeiro Internal Medicine Department, Hospital Amato Lusitano, Castelo Branco
  • Rosa Silva Internal Medicine Department, Hospital Amato Lusitano, Castelo Branco

dmdalves11@gmail.com

Keywords

Toxic epidermal necrolysis, Nikolsky’s sign, erythematous macules.

Abstract

A 63-year-old male patient suffered from myalgia, arthralgia cough and erythematous macules, with confluence to the thorax, limbs, thighs and the scrotum. The erythematous macules evolved to blisters with a positive Nikolsky’s sign. A cutaneous biopsy revealed satellite cell necrosis. Administration of immunoglobulins resulted in a favourable evolution of the cutaneous lesions. Toxic epidermal necrolysis (TEN) is a rare and potentially fatal mucocutaneous disease. Early recognition, diagnosis and therapy are of the utmost importance.

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References

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Published

2016-11-28

How to Cite

1.
Alves DD, Lourenço N, Franco D, Calmeiro E, Silva R. Toxic Epidermal Necrolyisis and Sepsis. EJCRIM [Internet]. 2016 Nov. 28 [cited 2026 Nov. 3];3(7). Available from: https://ejcrim.com/index.php/ejcrim/article/view/502