DOI: 10.12890/2024_004853

Spontaneous pneumomediastinum in a patient with marijuana use

Authors

  • Nutthakorn Horugsa Department of Pharmacology, Siriraj Hospital, Mahidol University, Bangkok, Thailand
  • Jiyeon Kim Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Samuel Kim Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Judy Lalmuanpuii Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA

Jiyeon.A.Kim@ttuhsc.edu

Keywords

Spontaneous pneumomediastinum, Macklin effect

Abstract

The Macklin effect plays an essential role in the pathogenesis of spontaneous pneumomediastinum. It is the process by which is there is a blunt alveolar rupture that leads to air dissection through the bronchopulmonary sheaths and spreads into the mediastinum. Theoretically, marijuana use can cause spontaneous pneumomediastinum indirectly by inducing rigorous vomiting. We report a case of a healthy 22-year-old male with a history of recent marijuana use who presented with pneumomediastinum and rhabdomyolysis concurrently. After a thorough investigation, we concluded that this patient had spontaneous pneumomediastinum due to the Macklin effect from severe vomiting.

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References

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Published

2024-09-24

Issue

Vol. 11 No. 10 (2024)

Categories

How to Cite

1.
Horugsa N, Kim J, Kim S, Lalmuanpuii J. Spontaneous pneumomediastinum in a patient with marijuana use. EJCRIM [Internet]. 2024 Sep. 24 [cited 2026 Nov. 3];11(10). Available from: https://ejcrim.com/index.php/ejcrim/article/view/4853

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