DOI: 10.12890/2021_002672

Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy

Authors

  • Noel Lorenzo Villalba Service de Médecine Interne, Diabète et Maladies Métaboliques, Hôpitaux Universitaires de Strasboug, France
  • Emmanuel Andrés Service de Médecine Interne, Diabète et Maladies Métaboliques, Hôpitaux Universitaires de Strasboug, France
  • Alain Meyer Service de Rhumatologie, Hôpitaux Universitaires de Strasbourg, France

noellorenzo@gmail.com

Abstract

We report a case of anti-HMGCR myopathy mimicking limb-girdle muscular dystrophy in a 27-year-old male patient with no history of statin intake and presenting with a chronic onset form over 3 years. Treatment with prednisone and methotrexate was initiated with an insufficient response, so intravenous immunoglobulin was added. One year after initial treatment was started, as levels of creatine kinase (CK) were >1000 U/l, treatment with rituximab was added. Despite a 3-year delay before treatment, muscle strength improved even though CK levels remain elevated.

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References

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Published

2021-06-08

Issue

Vol. 8 No. 6 (2021)

How to Cite

1.
Lorenzo Villalba N, Andrés E, Meyer A. Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy. EJCRIM [Internet]. 2021 Jun. 8 [cited 2026 Nov. 3];8(6). Available from: https://ejcrim.com/index.php/ejcrim/article/view/2672

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