Association of Multiple Myeloma and Giant Cell Arteritis – A Case Report

Authors

• Rui Marques Osório Internal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal
• Sérgio Pina Internal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal
• Teresa Salero Internal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal
• Margarida Viana Coelho Internal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal
• Domingos Sousa Internal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal
• Catarina Mendonça Internal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal

ruiosorio@gmail.com

Keywords

Abstract

Autoimmune diseases (AID) have been associated with a variety of lymphoproliferative disorders. Multiple myeloma (MM), one of the most common haematologic malignancies characterized by clonal proliferation of bone marrow plasma cells, has been associated with a range of autoimmune disorders. In this report, we described a case study of a patient admitted to our Internal Medicine Department for a bone marrow biopsy and myelogram due to a monoclonal peak observed by his general practitioner. However, at admission he presented typical giant cell arteritis (GCA) complaints, suggesting the coexistence of both diseases. The possible pathogenesis, as found in the literature, explaining the association will be discussed.