A case of chronic pulmonary aspergillosis due to pulmonary infarction, mimicking cryptogenic organising pneumonia
  • Saki Yanoma
    Department of Respiratory Medicine, Nagoya Tokushukai General Hospital, Kasugai City, Japan
  • Motoi Ugajin
    Department of Respiratory Medicine, Nagoya Tokushukai General Hospital, Kasugai City, Japan; Department of Respiratory Medicine and Allergology, Aichi Medical University, Nagakute City, Japan
  • Hiasanori Kani
    Department of Thoracic Surgery, Nagoya Tokushukai General Hospital, Kasugai City, Japan

Keywords

Pulmonary aspergillosis, pulmonary infarction, organising pneumonia

Abstract

A patient initially treated with corticosteroids for cryptogenic organising pneumonia following pulmonary infarction, developed a worsening condition with progressive cavitary formations in both lower lung lobes. Contrast-enhanced chest computed tomography revealed a pulmonary embolism, and serum anti-Aspergillus IgG antibody analysis yielded a strong positive result. Consequently, the patient was diagnosed with pulmonary infarction with Aspergillus infection; organising pneumonia in surrounding areas reflected the repair process. Following treatment with anticoagulants and antifungal agents, the patient was successfully discharged. Hence, pulmonary infarction should be considered in cases of refractory lung lesions.

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References

  • li>Kaptein FHJ, Kroft LJM, Hammerschlag G, Ninaber MK, Bauer MP, Huisman MV, et al. Pulmonary infarction in acute pulmonary embolism. Thromb Res 2021;202:162–169.
  • Islam M, Filopei J, Frank M, Ramesh N, Verzosa S, Ehrlich M, et al. Pulmonary infarction secondary to pulmonary embolism: an evolving paradigm. Respirology 2018;23:866–872.
  • Tunney R, Rodger K, Denning DW, Kosmidis C. Chronic pulmonary aspergillosis following pulmonary embolism. Med Mycol Case Rep 2018;23:20–22.
  • Hollenhorst MA, Battinelli EM. Thrombosis, hypercoagulable states, and anticoagulants. Prim Care 2016;43:619–635.
  • Smith NL, Denning DW. Underlying conditions in chronic pulmonary aspergillosis including simple aspergilloma. Eur Respir J 2011;37:865–872.
  • Narita J-I, Ito S, Terada M, Saitoh Y, Igarashi K-I, Nakano M, et al. Pulmonary artery involvement in Takayasu’s arteritis with lung infarction and pulmonary aspergillosis. J Clin Rheumatol 2002;8:260–264.
  • Patterson TF, Thompson GR 3rd, Denning DW, Fishman JA, Hadley S, Herbrecht R, et al. Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the Infectious Diseases Society of America. Clin Infect Dis 2016;63:e1–e60.
  • Salzer HJF, Reimann M, Oertel C, Davidsen JR, Laursen CB, Braeckel EV, et al. Aspergillus-specific IgG antibody for diagnosing chronic pulmonary aspergillosis compared to the reference standard. Clin Microbiol Infect 2023;29:1605.e1–1605.e4.
  • Cordier JF. Organising pneumonia. Thorax 2000;55:318–328.
  • Sakurai A, Yanai H, Ishida T, Kuwata H, Kamei K, Izumi S. Possible relationship between organizing pneumonia and chronic pulmonary aspergillosis: a case report and literature review. Respir Investig 2017;55:74–78.

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    Published: 2024-04-22
    Issue: 2024: LATEST ONLINE (view)

    How to cite:
    1.
    Yanoma S, Ugajin M, Kani H. A case of chronic pulmonary aspergillosis due to pulmonary infarction, mimicking cryptogenic organising pneumonia. EJCRIM 2024;11 doi:10.12890/2024_004501.