DOI: 10.12890/2014_000086

Is Aphtous Oral Ulceration Biopsy Always Useless?

Authors

  • Yohan N'Guyen Internal Medicine Department, Infective Diseases and Clinical Immunology, Robert Debré Hospital, Reims, France
  • Amélie Servettaz Internal Medicine Department, Infective Diseases and Clinical Immunology, Robert Debré Hospital, Reims, France
  • Florent Ehrhard Hepatology and Gastroenterology Department, Robert Debré Hospital, Reims, France
  • Firouze Bani-Sadr Internal Medicine Department, Infective Diseases and Clinical Immunology, Robert Debré Hospital, Reims, France
  • Michel Pluot Pathological Anatomy Laboratory, Robert Debré Hospital, Reims, France

yohan.nguyen@wanadoo.fr

Abstract

Objective: To report a case of Behc?et’s disease whose diagnosis was only confirmed thanks to an oral aphthous lesion biopsy.
Materials and methods: Conventional histopathological analysis of a biopsy of an aphthous oral lesion that had appeared two days previously.
Results: A small vein vasculitis with eosinophil and neutrophil granulocytes was evidenced. 
Conclusion: The presence of a small vein vasculitis was here strongly in favour of Behc?et's disease, whereas such a diagnosis was not confirmed according to the International Study Group’s criteria.

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References

  1. Scully C. Aphthous ulceration, N. Engl. J. Med.2006;355:165–172.
  2. International Study Group for Behçet’s Disease. Criteria for diagnosis of Behcet’s disease, Lancet 1990;335:1078–1080.
  3. Chen KR, Kahawara Y, Miyakawa S, Nishikawa T. Cutaneous vasculitis in Behcet's disease: a clinical and histopathologic study of 20 patients, J. Am. Acad. Dermatol. 1997;36:689–696.
  4. Melikoglu M, Kural-Seyahi E, Tascilar K, Yazici H. The unique features of vasculitis in Behçet’s syndrome, Clin. Rev. Allergy Immunol. 2008;35:40–46.

Published

2014-06-13

How to Cite

1.
N'Guyen Y, Servettaz A, Ehrhard F, Bani-Sadr F, Pluot M. Is Aphtous Oral Ulceration Biopsy Always Useless? EJCRIM [Internet]. 2014 Jun. 13 [cited 2026 Nov. 3];1(1). Available from: https://ejcrim.com/index.php/ejcrim/article/view/86