DOI: 10.12890/2017_000736
Amoxicillin Crystalluria: A Rare Side-Effect of a Commonly Prescribed Antibiotic
Authors
joraco12a@gmail.com
Keywords
Crystalluria, amoxicillin, "shock wheat" crystals, “broom like” crystalsAbstract
Although crystalluria is a frequent finding in the routine examination of urine, amoxicillin crystalluria is a rare event whose incidence remains unknown. Crystalluria caused by amoxicillin is very uncommon and may be asymptomatic or have severe renal implications. The authors describe the case of an 87-year-old female patient who presented with massive amoxicillin crystalluria due to poor hydration, low urinary pH and high intravenous amoxicillin dosage.
References
- Fogazzi GB. Crystalluria: a neglected aspect of urinary sediment analysis. Nephrol Dial Transplant 1996;11:379–387.
- Fogazzi GB, Cantù M, Saglimbini L, Daudon MA. A rare but possible cause of crystalluria. Nephrol Dial Transplant 2003;18:212–214.
- Jones P, Gaber L, Nilsson GR, et al. Acute renal failure following amoxycillin overdose. Clin Pediatr 1993;32:735–739.
- Sjovall J, Westerlund D, Alvan G. Renal excretion of intravenously infused amoxycillin and ampicillin.Br J Clin Pharmacol 1985;19:191–201.
- Hentzien M, Lambert D, Limelette A, N’Guyen Y, Robbins A, Lebrun D, et al. Macroscopic amoxicillin crystalluria. Lancet 2015;385(9984):2296.
- Van Noord C, Wulkan RW, van den Dorpel MA. Crystalluria. Neth J Med 2012;70:84, 87.