DOI: 10.12890/2026_007079
Identical critical left anterior descending artery stenosis in monozygotic twins
Authors
dan.Justo@sheba.health.gov.il
Keywords
Coronary artery disease, monozygotic twins, hypercholesterolemia, smoking, genetic predispositionAbstract
Introduction: Coronary artery disease (CAD) is a multifactorial condition influenced by both genetic predispositions and environmental exposures.
Case description: We present a pair of male monozygotic twins diagnosed with identical critical left anterior descending artery stenosis, suggesting a possible hereditary susceptibility involving this coronary segment. One twin presented with acute coronary syndrome while the other was diagnosed with CAD during screening prompted by his sibling’s diagnosis.
Conclusion: This report underscores the importance of early screening among genetically related individuals and contributes to the understanding of phenotypic variability in genetically identical patients with CAD.
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