DOI: 10.12890/2026_006099

Cardiac involvement as first manifestation of peripheral T-cell not otherwise specified lymphoma

Authors

  • Paula Awamleh García Cardiology Department, Hospital Universitario de Getafe, Madrid, Spain
  • Manuel Emilio Monguió Santín Cardiac Surgery Department, Hospital Universitario de la Princesa, Madrid, Spain
  • Carla López Martínez Pathology Department, Hospital Universitario de la Princesa, Madrid, Spain
  • Susana Hernández Muñiz Radiology Department, Hospital Universitario de la Princesa, Madrid, Spain
  • Miguel de la Serna Real de Asúa Cardiology Department, Hospital Universitario de Getafe, Madrid, Spain
  • Rosalía Alonso Trillo Haematology and Haemotherapy Department, Hospital Universitario de Getafe, Madrid, Spain
  • María Isabel Delgado Trillo Haematology and Haemotherapy Department, Hospital Universitario de Getafe, Madrid, Spain

paulaawamleh@yahoo.es

Keywords

Cardiac lymphoma, atrioventricular block, chemotherapy

Abstract

Cardiac involvement as the first manifestation of peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) is extremely rare. We report on a 72-year-old man with hypertension, dyslipidaemia and prediabetes who presented with acute pleuropericarditis, pericardial effusion and conduction abnormalities. Despite initial treatment, his condition worsened. Imaging revealed pericardial/myocardial infiltration and a right atrial mass. Biopsy confirmed PTCL-NOS (CD3+, CD5+, CD7+, high Ki-67). Complications included ileus, pulmonary embolism and neutropaenia. CHOP failed; GemOx was ineffective; he died from hypernatremia. This reported case emphasises the aggressive course, diagnostic challenges and poor treatment response of cardiac PTCL-NOS.

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References

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Published

2026-04-27

Issue

Vol. 13 No. 5 (2026)

Categories

How to Cite

1.
Awamleh García P, Monguió Santín ME, López Martínez C, Hernández Muñiz S, de la Serna Real de Asúa M, Alonso Trillo R, et al. Cardiac involvement as first manifestation of peripheral T-cell not otherwise specified lymphoma. EJCRIM [Internet]. 2026 Apr. 27 [cited 2026 Nov. 3];13(5). Available from: https://ejcrim.com/index.php/ejcrim/article/view/6099