DOI: 10.12890/2025_005846

Sertraline-induced urinary incontinence

Authors

  • Abdulaziz Muflih Abudasser Department of Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia 0000-0002-8265-757X

amabdulaziz@kku.edu.sa

Keywords

Sertraline, SSRI, urine incontinence

Abstract

Introduction: Sertraline is a widely prescribed selective serotonin reuptake inhibitor (SSRI) with a favourable safety profile, though rare adverse effects may occur.
Case description: We report the case of a 73-year-old woman with generalised anxiety disorder and panic disorder who developed new-onset urinary incontinence after initiation of sertraline. Symptoms improved with dose reduction but recurred at higher doses, suggesting a causal relationship. Management with clomipramine and solifenacin successfully resolved the urinary incontinence while maintaining psychiatric remission.
Discussion: Our case contributes to the limited literature by documenting an elderly female patient who developed urinary incontinence secondary to sertraline, confirmed through a temporal association, dose-–response relationship, and symptom resolution with targeted interventions.
Conclusion: This case highlights the importance of recognising uncommon SSRI side effects and tailoring management to balance efficacy and tolerability.

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References

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Published

2025-10-22

Issue

Vol. 12 No. 11 (2025)

Categories

How to Cite

1.
Abudasser AM. Sertraline-induced urinary incontinence. EJCRIM [Internet]. 2025 Oct. 22 [cited 2026 Nov. 3];12(11). Available from: https://ejcrim.com/index.php/ejcrim/article/view/5846