DOI: 10.12890/2026_005819

Pancreatic metastases from urothelial cancer

Authors

  • Maria Kyrkasiadou 2nd Propaedeutic Dept of Internal Medicine, National & Kapodistrian University of Athens, Attikon University Hospital, Chaidari, Greece
  • Ioannis S. Papanikolaou 2nd Propaedeutic Dept of Internal Medicine, National & Kapodistrian University of Athens, Attikon University Hospital, Chaidari, Greece
  • Ekaterini Politi Cytopathology Department, National and Kapodistrian University of Athens, Aretaieion University Hospital, Athens, Greece
  • Vasiliki Nikolaidou 2nd Propaedeutic Dept of Internal Medicine, National & Kapodistrian University of Athens, Attikon University Hospital, Chaidari, Greece
  • Konstantina Kakogianni 2nd Propaedeutic Dept of Internal Medicine, National & Kapodistrian University of Athens, Attikon University Hospital, Chaidari, Greece
  • Keisi Mara 2nd Propaedeutic Dept of Internal Medicine, National & Kapodistrian University of Athens, Attikon University Hospital, Chaidari, Greece
  • Aristotle Bamias 2nd Propaedeutic Dept of Internal Medicine, National & Kapodistrian University of Athens, Attikon University Hospital, Chaidari, Greece

v.k.nikolaidou@gmail.com

Keywords

Urothelial carcinoma, pancreatic metastasis, endoscopic ultrasound, fine needle biopsy

Abstract

Background: Urothelial carcinoma (UC) is a common malignancy that rarely metastasizes to the pancreas. Pancreatic masses in patients with UC present significant diagnostic challenges.
Case report: An elderly man with a history of nephroureterectomy for UC of the renal pelvis presented with lower back pain, nausea, and constipation. Imaging revealed local relapse and a solitary pancreatic mass. Endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) confirmed the diagnosis of metastatic UC. The patient was treated with carboplatin and gemcitabine and subsequently with pembrolizumab but experienced rapid progression and succumbed to his disease.
Conclusion: Pancreatic metastases from UC are extremely rare. Accurate diagnosis requires histological confirmation, and EUS-FNB provides a minimally invasive and effective method. Management should be individualized, and the role of multidisciplinary team involvement is critical.

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References

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Published

2026-01-28

Issue

Vol. 13 No. 2 (2026)

Categories

How to Cite

1.
Kyrkasiadou M, Papanikolaou IS, Politi E, Nikolaidou V, Kakogianni K, Mara K, et al. Pancreatic metastases from urothelial cancer. EJCRIM [Internet]. 2026 Jan. 28 [cited 2026 Nov. 3];13(2). Available from: https://ejcrim.com/index.php/ejcrim/article/view/5819