DOI: 10.12890/2025_005559

Thyroid storm in the shadows of multiple endocrine neoplasia (MEN) 2A: a case of overlapping endocrine emergencies

Authors

  • Ridda Khattak Department of Internal Medicine, Bayhealth Medical Center, Dover, USA
  • Enrique Cortez Department of Internal Medicine, Bayhealth Medical Center, Dover, USA
  • Madihah Alam Department of Internal Medicine, Bayhealth Medical Center, Dover, USA
  • Rohab Sohail Department of Internal Medicine, Bayhealth Medical Center, Dover, USA
  • Zaraq Khan Department of Internal Medicine, Indiana University School of Medicine Southwest, New Albany, USA
  • Maria Azhar Department of Pulmonology and Critical Care, Bayhealth Medical Center, Dover, USA

ridda_khattak@bayhealth.org

Keywords

Thyroid storm, phaeochromocytoma, MEN 2A, acute metabolic encephalopathy

Abstract

Thyroid storm is observed in patients with untreated Graves’ disease, typically triggered by stressors such as acute illness or recent surgery. This case presents a female with acute metabolic encephalopathy initially attributed to drug overdose and septic shock, later diagnosed with thyroid storm. Despite clinical stabilisation, the patient developed resistant hypertension and elevated metanephrine levels, raising suspicion for phaeochromocytoma and potential multiple endocrine neoplasia (MEN) 2A. This case highlights the importance of considering syndromic and autoimmune associations in complex endocrine presentations.

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References

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Published

2025-07-14

Issue

Vol. 12 No. 8 (2025)

Categories

How to Cite

1.
Khattak R, Cortez E, Alam M, Sohail R, Khan Z, Azhar M. Thyroid storm in the shadows of multiple endocrine neoplasia (MEN) 2A: a case of overlapping endocrine emergencies. EJCRIM [Internet]. 2025 Jul. 14 [cited 2026 Nov. 3];12(8). Available from: https://ejcrim.com/index.php/ejcrim/article/view/5559

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