DOI: 10.12890/2025_005544

Brugada ECG pattern in a Caucasian patient with severe hypothyroidism

Authors

  • Erminia De Cristofaro Internal Medicine and Hypertension Center, Sant’Anna Hospital Castelnovo ne’ monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
  • Maria Giulia Canè Internal Medicine and Hypertension Center, Sant’Anna Hospital Castelnovo ne’ monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
  • Davide Cunzi Internal Medicine and Hypertension Center, Sant’Anna Hospital Castelnovo ne’ monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
  • Giorgia Prampolini Internal Medicine and Hypertension Center, Sant’Anna Hospital Castelnovo ne’ monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
  • Silvia Daniela Umbertina Fedeli Internal Medicine and Hypertension Center, Sant’Anna Hospital Castelnovo ne’ monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
  • Aurelio Negro Internal Medicine and Hypertension Center, Sant’Anna Hospital Castelnovo ne’ monti, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy

erminia.decristofaro@ausl.re.it

Keywords

Brugada syndrome, hypothyroidism, ischaemic heart disease

Abstract

Brugada syndrome (BrS) is a disorder leading to potentially life-threatening ventricular arrhythmias in patients with an apparently normal heart. It mostly affects men of Asian descent, and the prevalence varies between ethnicities. Typical ECG abnormalities with no symptoms are referred to as the Brugada pattern, and hypothyroidism is a potential trigger of this. We report on a Caucasian man with severe hypothyroidism and Brugada ECG pattern, which normalised after starting replacement therapy. The association has been previously described in only a few patients.

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References

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Published

2025-08-18

How to Cite

1.
De Cristofaro E, Canè MG, Cunzi D, Prampolini G, Fedeli SDU, Negro A. Brugada ECG pattern in a Caucasian patient with severe hypothyroidism. EJCRIM [Internet]. 2025 Aug. 18 [cited 2026 Nov. 3];12(9). Available from: https://ejcrim.com/index.php/ejcrim/article/view/5544