DOI: 10.12890/2025_005294

Pulmonary tumour embolism from gastric adenocarcinoma causing respiratory and cardiac failure may not be identified on standard ante-mortem imaging

Authors

  • Konstantīns Ščerbakovs Department of Lung Diseases and Thoracic Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia; Riga Stradins University, Riga, Latvia
  • Valentīna Mihejeva Department of Lung Diseases and Thoracic Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia; Riga Stradins University, Riga, Latvia
  • Sergejs Dubencovs Department of Pathology, Pauls Stradins Clinical University Hospital, Riga, Latvia
  • Evelīna Stunda Department of Pathology, Pauls Stradins Clinical University Hospital, Riga, Latvia
  • Dace Žentiņa Department of Lung Diseases and Thoracic Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia; Riga Stradins University, Riga, Latvia

scerbakovs.k@gmail.com

Keywords

Pulmonary tumour embolism, lymphangitic carcinomatosis, gastric adenocarcinoma

Abstract

Pulmonary tumour embolism is severe complication of malignancy, often presenting with progressive dyspnoea and respiratory failure. Due to their non-specific symptoms and absence of clear imaging findings, diagnosis is frequently delayed or made post-mortem. This is a case of previously undiagnosed gastric adenocarcinoma presenting with rapidly worsening respiratory symptoms: hypoxaemia, pulmonary hypertension and heart failure. Standard imagining – computed tomography angiography and echocardiography – provide indirect evidence, definitive diagnosis of pulmonary tumour embolism confirmed post-mortem. This case highlights the diagnostic challenges associated with a pulmonary tumour embolism and underscores the importance of early suspicion of malignancy-related complications in cases of progressive respiratory and cardiac failure without radiographic evidence of pulmonary embolism.

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References

  1. Khachekian A, Shargh S, Arabian S. Pulmonary lymphangitic carcinomatosis from metastatic gastric adenocarcinoma: case report. J Am Osteopath Assoc 2015;115:332–337.
  2. Restrepo J, Carvajal-Fierro CA, Facundo H, González F, Ramírez AM, Beltran R, et al. Pleural and pulmonary dissemination patterns from gastric adenocarcinoma among patients with treated primary disease in Latin America. Front Surg 2022;9:969397.
  3. Belhassine M, Papakrivopoulou E, Venet C, Mestdagh C, Schroeven M. Gastric adenocarcinoma revealed by atypical pulmonary lymphangitic carcinomatosis. J Gastrointest Oncol 2018;9:1207–1212.
  4. Engel J, Auer J. Pulmonary tumour embolism and lymphangitis carcinomatosa: a case report and review of the literature. J Cardiothorac Surg 2022;17:105.
  5. Kamouh A, Nelson A, Vats S, Powell R Jr, Missov E. Pulmonary tumor thrombotic microangiopathy associated with right ventricular rupture and hemopericardium: a case report. J Cardiol Cases 2014;9:230–232.

Published

2025-03-26

How to Cite

1.
Ščerbakovs K, Mihejeva V, Dubencovs S, Stunda E, Žentiņa D. Pulmonary tumour embolism from gastric adenocarcinoma causing respiratory and cardiac failure may not be identified on standard ante-mortem imaging. EJCRIM [Internet]. 2025 Mar. 26 [cited 2026 Nov. 3];12(4). Available from: https://ejcrim.com/index.php/ejcrim/article/view/5294

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