DOI: 10.12890/2025_005248
Acute bowel perforation post-bowel preparation in a patient with connective tissue disease
Authors
OMARBRIJAWI@GMAIL.COM
Keywords
Bowel preparation, bowel perforation, connective tissue diseaseAbstract
Isosmotic oral agents are commonly used in bowel preparation due to their minimal side effects. However, bowel perforation is a rare and severe complication. Connective tissue disease and medications such as nonsteroidal anti-inflammatory drugs/steroids can weaken the colonic wall, which increases the risk of perforation. We present a case of a 67-year-old male with undifferentiated mixed connective tissue disease who developed a bowel perforation after administration of bowel prep. The patient initially presented to the emergency department with diffuse abdominal pain, with imaging showing evidence of perforation. Despite surgical and medical intervention, the patient passed away.
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