DOI: 10.12890/2025_005219

Oesophageal dysmotility in a patient with Charcot-Marie-Tooth disease: report and literature review

Authors

  • Mohammad Kloub Department of Internal Medicine, Saint Micheal’s Medical Center, Newark, USA
  • Abdul-Rahman I Abusalim Department of Internal Medicine, Division of Hospital Medicine, University of Wisconsin School of Medicine and Public Health, Madison, USA
  • Mohamed Eldesouki Department of Internal Medicine, Saint Micheal’s Medical Center, Newark, USA
  • Mohammad Abushanab Department of Internal Medicine, Saint Micheal’s Medical Center, Newark, USA
  • Byron Okwesili Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Micheal’s Medical Center, Newark, USA
  • Raed Atiyat Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Micheal’s Medical Center, Newark, USA
  • Yatinder Bains Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Micheal’s Medical Center, Newark, USA

mohammad_kloub98@yahoo.com

Keywords

Charcot-Marie-Tooth disease, dysphagia, smooth muscle, neurological disorder, aspiration pneumonia, oesophageal dysmotility

Abstract

Oesophageal dysmotility is a serious condition characterised by impaired coordination of oesophageal smooth muscle contractions, which can be secondary to a variety of causes including infection, inflammation and malignancy. The presenting symptoms are variable and include chest or epigastric pain, food regurgitation, heartburn or cough, making it difficult to distinguish. Diagnostic modalities and treatment strategies vary depending on the underlying cause. Once oesophageal dysmotility is suspected, a thorough evaluation is essential as the management strategies and prognosis of the condition differ significantly based on the underlying pathology. A multidisciplinary approach and clinical expertise are essential for optimal patient care and treatment. While neuromuscular disorders are associated with swallowing dysfunction due to oropharyngeal muscle involvement, oesophageal smooth muscles involvement is rare. This case highlights the importance of careful and frequent evaluation of both respiratory and gastrointestinal smooth muscle function, particularly in patients with chronic neurological disorders.

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References

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Published

2025-03-17

Issue

Vol. 12 No. 4 (2025)

Categories

How to Cite

1.
Kloub M, Abusalim A-RI, Eldesouki M, Abushanab M, Okwesili B, Atiyat R, et al. Oesophageal dysmotility in a patient with Charcot-Marie-Tooth disease: report and literature review. EJCRIM [Internet]. 2025 Mar. 17 [cited 2026 Nov. 4];12(4). Available from: https://ejcrim.com/index.php/ejcrim/article/view/5219

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