DOI: 10.12890/2016_000500

Dermatomyositis Associated with Sarcoidosis: Two Cases

Authors

  • Paschalis Sidiras Department of Rheumatology and Physical Medicine, Hôpital Erasme, Université Libre de Bruxelles, Brussels
  • Frédéric Vandergheynst Department of Internal Medicine, Hôpital Erasme, Université Libre de Bruxelles, Brussels
  • Laurine Verset Department of Anatomic Pathology, Hôpital Erasme, Université Libre de Bruxelles, Brussels
  • Hazim Kadhim Neuropathology Unit, Department of Anatomic Pathology, CHU-Brugmann, Université Libre de Bruxelles, Brussels
  • Muhammad Shahnawaz Soyfoo Department of Rheumatology and Physical Medicine, Hôpital Erasme, Université Libre de Bruxelles, Brussels

paschalis.sidiras@erasme.ulb.ac.be

Keywords

Sarcoidosis, Dermatomyositis, auto-antibodies

Abstract

Dermatomyositis (DM) and sarcoidosis are two idiopathic systemic disorders. Reports of patients with both conditions are extremely rare. Here we describe two patients who presented with DM and DM-associated antibodies, and later developed biopsy-proven sarcoidosis. There are increasing reports of the occurrence of sarcoidosis in the context of autoimmune diseases. These observations might imply similarities in the pathogenetic mechanisms.

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References

  1. Judson MA, Shapiro L, Freitas S, Polychronopoulos VS, Highland KB. Concomitant sarcoidosis and a connective tissue disease: review of the clinical findings and postulations concerning their association. Resp Med 2013;107:1453–1459.
  2. Facco M, Cabrelle A, Teramo A, Olivieri V, Gnoato M, Teolato S, et al. Sarcoidosis is a Th1/Th17 multisystem disorder. Thorax 2011;66:144–150.
  3. Tournadre A, Miossec P. Interleukin-17 in inflammatory myopathies. Curr Rheumatol Rep 2012;14:252–256.
  4. Venalis P, Lundberg IE. Immune mechanisms in polymyositis and dermatomyositis and potential targets for therapy. Rheumatology (Oxford) 2014;53:397–405.
  5. Chen ES, Moller DR. Etiologies of sarcoidosis. Clin Rev Allergy Immunol 2015;49:6–18.

Published

2017-01-27

Issue

Vol. 4 No. 1 (2017)

How to Cite

1.
Sidiras P, Vandergheynst F, Verset L, Kadhim H, Soyfoo MS. Dermatomyositis Associated with Sarcoidosis: Two Cases. EJCRIM [Internet]. 2017 Jan. 27 [cited 2026 Nov. 3];4(1). Available from: https://ejcrim.com/index.php/ejcrim/article/view/500

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