DOI: 10.12890/2016_000492

Central Retinal Vein Occlusion Revealing Coelic Disease

Authors

  • Hana ZOUBEIDI Department of Internal Medicine, Rabta hospital, Tunis, Tunisia
  • Thouraya Ben Salem Department of Internal Medicine, Rabta Hospital, Tunis, Tunisia
  • Imed Ben Ghorbel Department of Internal Medicine, Rabta Hospital, Tunis, Tunisia
  • Mohamed Habib Houman Department of Internal Medicine, Rabta Hospital, Tunis, Tunisia

hanazoubeidi@yahoo.com

Keywords

Coeliac disease, Malabsorption Syndromes, retinal vein occlusion, thrombosis.

Abstract

Introduction: Thrombosis has been widely reported in coeliac disease (CD) but central retinal vein occlusion (CRVO) is rarely described.

Case presentation: A 27-year-old woman presented with acute visual loss and was diagnosed with CRVO. Her protein S and protein C levels were low and CD was diagnosed on the basis of endoscopic, immunological and histological results. A gluten-free diet resulted in favourable evolution.

Conclusion: CD should be considered in young patients with thrombosis, especially if in an unusual location. Treatment is based on a gluten-free diet.

View the entire article

Downloads

References

  1. Malamut G, Cellier C. Celiac disease. Rev Med Interne 2010;31:428–433.
  2. Berthoux E, Fabien N, Chayvialle JA, Ninet J, Durieu I. Adult celiac disease with thrombosis: a case series of seven patients. Role of thrombophilic factors. Rev Med Interne 2011;32:600–604.
  3. Lee ES, Pulido JS. Nonischemic central retinal vein occlusion associated with celiac disease. Mayo Clin Proc 2005;80:157.
  4. Jomni T, Bellakhal S, Abouda M, Abdelaali I, Douggui H. An atypical presentation of celiac disease: central retinal vein occlusion. Pan Afr Med J 2015;22:300.
  5. Wassim H, Wady BJ, Houda L, Besma BA, Kadija B, Hela K et al. Central retinal vein occlusion secondary to celiac disease: a case report. J Fr Ophtalmol 2016;39:e157–159.
  6. Ray JG. Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease. Arch Intern Med 1998;158:2101–2106.
  7. Saibeni S, Lecchi A, Meucci G, Cattaneo M, Tagliabue L, Rondonotti E, et al. Prevalence of hyperhomocysteinemia in adult gluten-sensitive enteropathy at diagnosis: role of B12, folate, and genetics. Clin Gastroenterol Hepatol 2005;3:574–580.
  8. Halfdanarson TR, Litzow MR, Murray JA. Hematologic manifestations of celiac disease. Blood 2007;109:412–421.
  9. Lerner A, Blank M. Hypercoagulability in celiac disease—an update. Autoimmun Rev 2014;13:1138–1141.
  10. Francis PJ, Stanford MR, Graham EM. Dehydration is a risk factor for central retinal vein occlusion in young patients. Acta Ophthalmol Scand 2003;81:415–416.

Published

2016-11-28

How to Cite

1.
ZOUBEIDI H, Ben Salem T, Ben Ghorbel I, Houman MH. Central Retinal Vein Occlusion Revealing Coelic Disease. EJCRIM [Internet]. 2016 Nov. 28 [cited 2026 Nov. 3];3(7). Available from: https://ejcrim.com/index.php/ejcrim/article/view/492

Most read articles by the same author(s)