DOI: 10.12890/2024_004762

Facial venous tumour thrombus from submandibular gland mucoepidermoid carcinoma: an atypical tumour spread in head and neck cancer

Authors

  • Mariam Malik Radiology, INMOL Cancer Hospital, Lahore, Pakistan
  • Rana Bilal Idrees Radiology, INMOL Cancer Hospital, Lahore, Pakistan
  • Zeeshan Rashid Mirza Radiology, INMOL Cancer Hospital, Lahore, Pakistan
  • Sharifa Sikandar Radiology, INMOL Cancer Hospital, Lahore, Pakistan
  • Saba Nawaz Radiology, INMOL Cancer Hospital, Lahore, Pakistan
  • Maham Khalid Radiology, INMOL Cancer Hospital, Lahore, Pakistan
  • Muhammad Hamid Chaudhary Cardiovascular Surgery, CPEIC, Multan, Pakistan 0000-0002-1634-011X

dr.hamid632@gmail.com

Keywords

Mucoepidermoid carcinoma, facial veins, cerebral venous thrombosis, submandibular gland neoplasms, salivary gland neoplasms

Abstract

Background: Tumour thrombus of the facial vein is an exceedingly rare complication arising from mucoepidermoid carcinoma of the salivary glands. Early detection is pivotal for appropriate management, as delays can lead to metastatic disease, worsening the prognosis.
Case description: We present a case involving a 76-year-old male with a history of mucoepidermoid carcinoma of the right submandibular gland, previously treated with surgical resection and radiotherapy. The patient, a long-term worker in a rubber factory, presented with a painless, firm swelling in the right cheek, persisting for three months. Contrast-enhanced computed tomography (CECT) showed distended facial vein with enhancing thrombus confirmed by sonographic correlation demonstrating intralesional vascularity. Cannon ball pulmonary nodules were also noted. Radiological findings led to a core biopsy, confirming tumor thrombosis of the facial vein due to mucoepidermoid carcinoma. However, the patient declined a biopsy of the pulmonary nodules, and has been referred to oncology for further management.
Conclusions: This case highlights the critical importance of considering venous tumour thrombus in patients with previous salivary gland malignancies presenting with new or persistent facial swellings. It emphasises the role of advanced imaging techniques in the early identification of this rare entity. Additionally, it stresses the need for healthcare providers to engage in thorough discussions with patients about the potential consequences of forgoing recommended treatments, reinforcing the need for vigilance in monitoring such patients.

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References

  1. Yap D, Dragan A, Weller A, Tatla T. Rare case of venous tumour thrombus from acinic cell carcinoma of the parotid gland. Ann R Coll Surg Engl 2020;102:e161–e166.
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Published

2024-08-21

How to Cite

1.
Malik M, Idrees RB, Mirza ZR, Sikandar S, Nawaz S, Khalid M, et al. Facial venous tumour thrombus from submandibular gland mucoepidermoid carcinoma: an atypical tumour spread in head and neck cancer. EJCRIM [Internet]. 2024 Aug. 21 [cited 2026 Nov. 3];11(9). Available from: https://ejcrim.com/index.php/ejcrim/article/view/4762

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