DOI: 10.12890/2024_004528
Recurrent infective endocarditis of the mitral valve after orthotopic heart transplantation
Authors
benko36@uniba.sk
Keywords
immunosuppression, haemodialysis, antibiotics, bacteraemia, catheter sepsisAbstract
Introduction: Orthotopic heart transplantation is the gold standard for the treatment of advanced heart failure in the absence of contraindications. Infective endocarditis is a rare complication in patients after heart transplantation. The treatment of endocarditis after heart transplantation is challenging since there is a need for ongoing immunosuppression.
Case description: We present the case of a 51-year-old orthotopic heart transplant recipient enrolled in a chronic dialysis program, in whom we diagnosed and successfully treated recurrent infective endocarditis of the mitral valve caused by Enterococcus and Enterobacter species. Despite the complicated course of the disease, the treatment was successful.
Conclusions: Recurrent infective endocarditis after heart transplantation can be treated successfully with a multidisciplinary approach and robust antimicrobial therapy.
References
- Martínez-Sellés M, Tattevin P, Valerio-Minero M, de Alarcón A, Fariñas MC, Mirabet-Pérez S, et al. Infective endocarditis in patients with heart transplantation. Int J Cardiol 2021;328:158-162.
- Jordan AM, Tatum R, Ahmad D, Patel SV, Maynes EJ, Weber MP, et al. Infective endocarditis following heart transplantation: A systematic review. Transplant Rev 2022;36:100672.
- Pericàs JM, Llopis J, Jiménez-Exposito MJ, Kourany WM, Almirante B, Carosi G, et al. Infective Endocarditis in Patients on Chronic Hemodialysis. J Am Coll Cardiol 2021;77:1629-1640.
- Ioannou P, Vamvoukaki R, Kofteridis DP. Infective endocarditis by Enterobacter cloacae: a systematic review and meta-analysis. J Chemother 2022;34:1-8.
- Karasahin O, Yildiz Z, Unal O, Arslan U. A rare cause of healthcare-associated infective endocarditis: Enterobacter cloacae. IDCases 2018;12:18-20.