DOI: 10.12890/2024_004503

Lacrimal sac diffuse large B-cell lymphoma presenting as sudden-onset binocular diplopia

Authors

  • Antoine Jeri-Yabar Department of Internal Medicine, Icahn School of Medicine at Mount Sinai Beth Israel, New York, USA
  • Liliana Vittini-Hernandez Department of Internal Medicine, Icahn School of Medicine at Mount Sinai Beth Israel, New York, USA
  • Bharati Dev Department of Internal Medicine, Icahn School of Medicine at Mount Sinai Beth Israel, New York, USA
  • Marissa Patel Department of Internal Medicine, Icahn School of Medicine at Mount Sinai Beth Israel, New York, USA
  • Meihuan Lin Department of Internal Medicine, Icahn School of Medicine at Mount Sinai Beth Israel, New York, USA

antoinejeri96@gmail.com

Keywords

Diffuse large B-cell lymphoma, ocular adnexal lymphoma, diplopia

Abstract

Introduction: Diffuse large B-cell lymphoma (DLBCL) is a prevalent subtype of non-Hodgkin lymphoma (NHL) affecting predominantly elderly individuals.
Case description: A 68-year-old man with a history of hypertension, hyperlipidaemia and a small pituitary gland tumour presented with sudden-onset binocular diplopia and right-eye blurry vision. A magnetic resonance imaging (MRI) of the brain revealed enhancing soft tissue in the right superolateral orbit inseparable from the lacrimal gland, extending medially to the right superior rectus muscle and soft tissue. Further scanning showed widespread metastasis to the bilateral retroperitoneal lymph nodes, adrenal gland, spine and lymph nodes in the neck. A biopsy of the lacrimal gland confirmed DLBCL.
Conclusion: Primary lacrimal gland DLBCL is a rare and delayed diagnosis that often stems from the resemblance of its clinical manifestations to more benign conditions such as dacryocystitis, dacryostenosis or mucocele. Timely recognition and accurate diagnosis are essential for initiating appropriate treatment and improving patient outcomes.

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References

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Published

2024-05-14

Issue

Vol. 11 No. 6 (2024)

Categories

How to Cite

1.
Jeri-Yabar A, Vittini-Hernandez L, Dev B, Patel M, Lin M. Lacrimal sac diffuse large B-cell lymphoma presenting as sudden-onset binocular diplopia. EJCRIM [Internet]. 2024 May 14 [cited 2026 Nov. 3];11(6). Available from: https://ejcrim.com/index.php/ejcrim/article/view/4503