DOI: 10.12890/2024_004373

The response of osmotic demyelination syndrome to plasmapheresis in a patient presenting with catatonia after correction of hyponatraemia in hyperemesis gravidarum

Authors

  • Vimonsri Rangsrisaeneepitak Division of Endocrinology and Metabolism, Department of Medicine, Burapha University, Chonburi, Thailand 0000-0001-5361-5648
  • Arnant Tekarnjnavanit Department of Medicine, Burapha University, Chonburi, Thailand
  • Pattarapol Kanjanapipatkul Division of Neurology, Department of Medicine, Burapha University, Chonburi, Thailand
  • Sukrisd Koowattanatianchai Division of Cardiology, Department of Medicine, Burapha University, Chonburi, Thailand

sukrisd.ko@go.buu.ac.th

Keywords

Osmotic demyelination syndrome, catatonia, hyponatraemia, hyperemesis gravidarum, plasmapheresis

Abstract

Osmotic demyelination syndrome (ODS) is a disorder characterised by the widespread development of demyelination in both pontine and extrapontine regions. It has been recognised as a complication arising from the rapid correction of hyponatraemia. This study presents the case of a 20-year-old Thai female patient at 10 weeks gestation, exhibiting an initial presentation of catatonia – an uncommon manifestation of ODS. The patient developed symptoms following the rapid correction of hyponatraemia in the context of hyperemesis gravidarum. Magnetic resonance imaging (MRI) of the brain revealed a trident or bat-wing-shaped pattern in T2-weighted and fluid-attenuated inversion recovery (FLAIR) sequences at the central pons. The patient underwent five cycles of plasmapheresis and received rehabilitation, leading to clinical improvement.

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Published

2024-03-11

Issue

Vol. 11 No. 4 (2024)

Categories

How to Cite

1.
Rangsrisaeneepitak V, Tekarnjnavanit A, Kanjanapipatkul P, Koowattanatianchai S. The response of osmotic demyelination syndrome to plasmapheresis in a patient presenting with catatonia after correction of hyponatraemia in hyperemesis gravidarum. EJCRIM [Internet]. 2024 Mar. 11 [cited 2026 Nov. 3];11(4). Available from: https://ejcrim.com/index.php/ejcrim/article/view/4373

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