DOI: 10.12890/2024_004297

A rare case of an elderly male with progression to chronic myeloid leukaemia secondary to chronic lymphocytic leukaemia

Authors

  • Sakditad Saowapa Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Watsachon Pangkanon Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Yaw Adu School of Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Nattanicha Chaisrimaneepan Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Diego Olavarria Bernal Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Natchaya Polpichai Department of Internal Medicine, Louis A Weiss Memorial Hospital, Chicago, USA
  • Pharit Siladech Internal Medicine Department, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Jasmine Sekhon Department of Hematology and Oncology, Texas Tech University Health Sciences Center, Lubbock, USA

s.sakditadmd@gmail.com

Keywords

Coexisting CLL/CML, chronic lymphocytic leukaemia, chronic myeloid leukaemia, dasatinib

Abstract

Chronic lymphocytic leukaemia (CLL) is a lymphoproliferative disorder characterised by an accumulation of monoclonal B lymphocytes, with an increased risk of secondary cancers. The coexistence of CLL and chronic myeloid leukaemia (CML) is a rare phenomenon, with three main types being classified: CML preceding CLL, CLL preceding CML and simultaneous occurrence. The coexistence of these chronic leukaemias poses a complex clinical challenge, with the underlying mechanisms of their association remaining enigmatic. Here, we present a report of an elderly male with a long history of CLL, who was subsequently diagnosed with secondary CML.

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Published

2024-03-01

Issue

Vol. 11 No. 4 (2024)

Categories

How to Cite

1.
Saowapa S, Pangkanon W, Adu Y, Chaisrimaneepan N, Olavarria Bernal D, Polpichai N, et al. A rare case of an elderly male with progression to chronic myeloid leukaemia secondary to chronic lymphocytic leukaemia. EJCRIM [Internet]. 2024 Mar. 1 [cited 2026 Nov. 3];11(4). Available from: https://ejcrim.com/index.php/ejcrim/article/view/4297

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