DOI: 10.12890/2023_004168

A rare convergence: adult-onset Langerhans cell histiocytosis and HIV infection

Authors

  • Andronikos Spyrou First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece
  • Michalis Ploumidis First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece
  • Sofia Nanousi First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece
  • Charis Roumbas Pathology Department, General Hospital of Athens ‘G. Gennimatas’, Athens, Greece
  • Georgios Adamis First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece
  • Myrto Astriti First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece

andronikos_00@hotmail.com

Keywords

Langerhans cell histiocytosis, adult-onset, HIV

Abstract

While primarily described in children, adult-onset Langerhans cell histiocytosis (LCH) has been reported, albeit infrequently. In the present scenario, we unveil a unique case of adult-onset LCH in an HIV-infected individual. After the diagnosis was made, the patient was successfully treated and demonstrated total disease remission. This case illustrates the diagnostic challenge that rare clinical entities such as LCH pose, especially in the context of an untreated HIV infection. Furthermore, the complexity of treating adult-onset Langerhans cell histiocytosis in an HIV-positive patient is highlighted, with emphasis given on a multidisciplinary approach.

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References

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Published

2023-11-24

Issue

Vol. 10 No. 12 (2023)

Categories

How to Cite

1.
Spyrou A, Ploumidis M, Nanousi S, Roumbas C, Adamis G, Astriti M. A rare convergence: adult-onset Langerhans cell histiocytosis and HIV infection. EJCRIM [Internet]. 2023 Nov. 24 [cited 2026 Nov. 4];10(12). Available from: https://ejcrim.com/index.php/ejcrim/article/view/4168