DOI: 10.12890/2022_003706

Refractory Shock Secondary to Denosumab-induced Severe Hypocalcaemia

Authors

  • Nouran Eshak Geriatric Division, Family Medicine Department, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
  • Mahmoud Abdelnabi Internal Medicine Department, Texas Tech University Health Sciences Center, Lubbock, Texas
  • Juthipong Benjanuwattra Internal Medicine Department, Texas Tech University Health Sciences Center, Lubbock, Texas
  • Amr Ismail Internal Medicine Department, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
  • Natnicha Leelaviwat Internal Medicine Department, Texas Tech University Health Sciences Center, Lubbock, Texas
  • Zeyad Elharabi Internal Medicine Department, Texas Tech University Health Sciences Center, Lubbock, Texas
  • John Culberson Geriatric Division, Family Medicine Department, Texas Tech University Health Sciences Center, Lubbock, Texas, USA

nouran91@yahoo.com

Keywords

Refractory shock, cardiogenic shock, denosumab, severe hypocalcaemia

Abstract

Denosumab is one of the most commonly used antiresorptive drugs for osteoporosis treatment and the prevention of skeletal-related events in cancer patients. The purpose of this case report is to highlight potentially life-threatening severe hypocalcaemia as a side effect of denosumab complicated by refractory shock that failed to respond to medical management including intravenous calcium, vasopressors and inotropes in an elderly man with a history of prostatic cancer.

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References

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Published

2022-12-23

Issue

Vol. 9 No. 12 (2022)

How to Cite

1.
Eshak N, Abdelnabi M, Benjanuwattra J, Ismail A, Leelaviwat N, Elharabi Z, et al. Refractory Shock Secondary to Denosumab-induced Severe Hypocalcaemia. EJCRIM [Internet]. 2022 Dec. 23 [cited 2026 Nov. 3];9(12). Available from: https://ejcrim.com/index.php/ejcrim/article/view/3706

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