DOI: 10.12890/2021_002833

Rifampicin-Induced Nephrotoxicity in a Tuberculosis Patient: Treatment Dilemma?

Authors

  • Antonio Grilo Novais Internal Medicine Department, Centro Hospitalar Tondela-Viseu, E.P.E, Portugal
  • Cláudio Silva Infectious Diseases Department, Centro Hospitalar Universitário São João, Porto, Portugal
  • Ana Rita Coelho Pathology Department, Centro Hospitalar Universitário São João, Porto, Portugal
  • Roberto Silva Pathology Department, Centro Hospitalar Universitário São João, Porto, Portugal
  • Ana Cláudia Carvalho Infectious Diseases Department, Hospital de Braga, Braga, Portugal

7875@hstviseu.min-saude.pt

Keywords

Acute tubulointerstitial nephritis, rifampicin-induced, tuberculosis

Abstract

Acute kidney injury related to rifampin is usually a clinical diagnosis. We report a case of a man being treated for pulmonary tuberculosis with acute tubulointerstitial nephritis related to rifampicin.

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References

  1. Manika K, Tasiopoulou K, Vlogiaris L, Lada M, Papaemmanouil S, Zarogoulidis K, et al. Rifampicin-associated acute renal failure and hemolysis: a rather uncommon but severe complication.Ren Fail 2013;35(8):1179–1181.
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  3. Joyce E, Glasner P, Ranganathan S, Swiatecka-Urban A. Tubulointerstitial nephritis: diagnosis, treatment, and monitoring. Pediatr Nephrol 2017;32(4):577–587.
  4. Clarkson MR, Giblin L, O'Connell FP, O'Kelly P, Walshe JJ, Conlon P, et al. Acute interstitial nephritis: clinical features and response to corticosteroid therapy. Nephrol Dial Transplant 2004;19(11):2778–2783.
  5. González E, Gutiérrez E, Galeano C, Chevia C, de Sequera P, Bernis C, et al. Early steroid treatment improves the recovery of renal function in patients with drug-induced acute interstitial nephritis. Kidney Int 2008;73(8):940–946.

Published

2021-10-14

Issue

Vol. 8 No. 10 (2021)

How to Cite

1.
Grilo Novais A, Silva C, Coelho AR, Silva R, Carvalho AC. Rifampicin-Induced Nephrotoxicity in a Tuberculosis Patient: Treatment Dilemma? EJCRIM [Internet]. 2021 Oct. 14 [cited 2026 Nov. 3];8(10). Available from: https://ejcrim.com/index.php/ejcrim/article/view/2833

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