DOI: 10.12890/2021_002571

Pantoprazole: An Unusual Suspect in a Patient with Fever

Authors

  • Nuno Melo Internal Medicine Department, Centro Hospitalar e Universitário de São João, Porto, Portugal
  • Sílvia Policarpo Infectious Disease Department, Centro Hospitalar e Universitário de São João, Porto, Portugal
  • Manuela Dias Internal Medicine Department, Centro Hospitalar e Universitário de São João, Porto, Portugal
  • Jorge Almeida Internal Medicine Department, Centro Hospitalar e Universitário de São João, Porto, Portugal

nunnomello@gmail.com

Keywords

Drug fever, acute hepatitis, pantoprazole

Abstract

Drugs can cause fever of unknown origin. Drug fever is a diagnosis of exclusion and can lead to unnecessary investigations and prolonged hospitalization. Any drug can be responsible. Here, we describe the case of a woman admitted because of acute hepatitis. Pantoprazole was started for stress ulcer prophylaxis when she was admitted to the ICU. Fever developed a few days later and an extensive diagnostic work-up was negative. Fever remitted after pantoprazole discontinuation and the diagnosis of drug fever was established.

View the entire article

Downloads

References

  1. Patel RA, Gallagher JC. Drug fever. Pharmacotherapy 2010;30(1):57–69.
  2. Bernal W, Auzinger G, Dhawan A, Wendon J. Acute liver failure. Lancet 2010;376(9736):190–201.
  3. Schiller D, Maieron A, Schöfl R, Donnerer J. Drug fever due to a single dose of pantoprazole.Pharmacology 2014;94(1–2):78–79.
  4. Harris LF, Holdsambeck HK. Drug fever--surprisingly common and costly. Ala Med 1986;56(3):19–22.
  5. Cunha BA. Antibiotic side effects. Med Clin North Am 2001;85(1):149–185.

Published

2021-05-28

How to Cite

1.
Melo N, Policarpo S, Dias M, Almeida J. Pantoprazole: An Unusual Suspect in a Patient with Fever. EJCRIM [Internet]. 2021 May 28 [cited 2026 Nov. 3];8(5). Available from: https://ejcrim.com/index.php/ejcrim/article/view/2571

Most read articles by the same author(s)

1 2 > >>