DOI: 10.12890/2021_002511

Disseminated Blastomycosis Presenting with Spontaneous Coronary Artery Dissection

Authors

  • Rahul Sehgal Department of Rheumatology, Mayo Clinic Alix School of Medicine, Mayo Clinic Health System, Eau Claire, Wisconsin, USA
  • D Fearghas O'Cochlain Department of Cardiovascular Medicine, Mayo Clinic Alix School of Medicine, Mayo Clinic Health System, Eau Claire, Wisconsin, USA
  • Andrew Virata Department of Pathology, Mayo Clinic Alix School of Medicine, Mayo Clinic Health System, Eau Claire, Wisconsin, USA
  • Gurpreet Singh Department of Cardiovascular Medicine, Mayo Clinic Alix School of Medicine, Mayo Clinic Health System, Eau Claire, Wisconsin, USA

sehgal.rahul@mayo.edu

Keywords

Spontaneous coronary artery dissection, ST-elevation myocardial infarction, blastomycosis

Abstract

Spontaneous coronary artery dissection (SCAD) is increasingly recognized as an important cause of acute coronary syndrome (ACS) and myocardial infarction (MI) in individuals with few or no known atherosclerotic risk factors. While systemic autoimmune inflammatory disorders are associated with precipitating SCAD, the role of infection-induced systemic inflammation in SCAD is not well defined. We present the case of a 49-year-old Caucasian woman with ST-elevation myocardial infarction (STEMI) diagnosed as SCAD from a severe systemic inflammatory response related to disseminated blastomycosis. Punch biopsy of a skin lesion and synovial fluid culture confirmed Blastomyces dermatitidis. This case suggests the possibility of systemic infection-induced inflammation as a precipitating factor in SCAD pathogenesis similar to autoimmune inflammatory disorders.

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References

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Published

2021-04-23

Issue

Vol. 8 No. 4 (2021)

How to Cite

1.
Sehgal R, O'Cochlain DF, Virata A, Singh G. Disseminated Blastomycosis Presenting with Spontaneous Coronary Artery Dissection. EJCRIM [Internet]. 2021 Apr. 23 [cited 2026 Nov. 3];8(4). Available from: https://ejcrim.com/index.php/ejcrim/article/view/2511

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