DOI: 10.12890/2021_002449

Delayed Recognition of Levetiracetam-induced Pancytopenia

Authors

  • Mohammad Ammad Ud Din Internal Medicine, Rochester General Hospital, Rochester, New York, USA
  • Syed Ather Hussain Internal Medicine, Rochester General Hospital, Rochester, New York, USA
  • Amy Bodrog Hematology/Oncology, Rochester General Hospital, Rochester, New York, USA

ammadahr@gmail.com

Keywords

Drug-induced-pancytopenia, thrombocytopenia, levetiracetam, hematology, anti-epileptics

Abstract

Blood dyscrasias associated with levetiracetam use can be difficult to identify, especially when other potential differential diagnoses are concurrently present. Here we present a 57-year-old man with metastatic adenocarcinoma of unknown primary origin on levetiracetam who initially presented with an in-stent thrombosis of the right external iliac vein and then developed worsening thrombocytopenia followed by pancytopenia. Levetiracetam was not identified as the culprit until other causes like platelet consumption, heparin-induced thrombocytopenia, idiopathic immune thrombocytopenic purpura, and bone marrow involvement by metastatic disease were ruled out.

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References

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Published

2021-03-30

Issue

Vol. 8 No. 3 (2021)

How to Cite

1.
Ammad Ud Din M, Ather Hussain S, Bodrog A. Delayed Recognition of Levetiracetam-induced Pancytopenia. EJCRIM [Internet]. 2021 Mar. 30 [cited 2026 Nov. 3];8(3). Available from: https://ejcrim.com/index.php/ejcrim/article/view/2449

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