DOI: 10.12890/2021_002448

Granulomatosis with Polyangiitis: Recurrence or Treatment Consequences?

Authors

  • Andreia Diegues Internal Medicine Department, Unidade Local de Saúde do Nordeste, Portugal
  • Joana Tavares Nephrology Department, Centro Hospitalar Universitário do Porto, Portugal
  • Diogo Sá athological Anatomy Department, Centro Hospitalar Universitário do Porto, Portugal
  • João Oliveira Nephrology Department, Centro Hospitalar Universitário do Porto, Portugal
  • Diana Fernandes Internal Medicine Department, Unidade Local de Saúde do Nordeste, Portugal
  • Josefina Santos Nephrology Department, Centro Hospitalar Universitário do Porto, Portugal
  • Guillerme Rocha Nephrology Department, Centro Hospitalar Universitário do Porto, Portugal

andreiadiegues@gmail.com

Keywords

ANCA-PR3-associated vasculitis, granulomatosis with polyangiitis, intracranial hypertension, lung nodules

Abstract

Granulomatosis with polyangiitis (GPA) is the most common antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). We describe the case of a 38-year-old woman with relapsing GPA who presented with intracranial hypertension, followed by the appearance of cavitated lung nodules despite treatment with azathioprine. Clinical improvement and ANCA titre reduction were observed after rituximab treatment. We report a rare form of GPA relapse and highlight the challenge of following-up patients with GPA, in whom can be hard to distinguish relapse from the consequences of long-term immunosuppression.

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References

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Published

2021-04-22

Issue

Vol. 8 No. 4 (2021)

How to Cite

1.
Diegues A, Tavares J, Sá D, Oliveira J, Fernandes D, Santos J, et al. Granulomatosis with Polyangiitis: Recurrence or Treatment Consequences? EJCRIM [Internet]. 2021 Apr. 22 [cited 2026 Nov. 3];8(4). Available from: https://ejcrim.com/index.php/ejcrim/article/view/2448

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