DOI: 10.12890/2020_002026

Radiotherapy-Associated Paraneoplastic Pemphigus and Its Complications in a Patient with Nasopharyngeal Carcinoma

Authors

  • Ali Hamza Khair Department of Internal Medicine, Shifa International Hospital, Islamabad, Pakistan
  • Aimen Asim Dar Department of Internal Medicine, Shifa International Hospital, Islamabad, Pakistan
  • Abu Baker Sheikh Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA
  • Aamir Iftikhar Malik Department of Pulmonology & Critical Care, Shifa International Hospital, Islamabad, Pakistan

sahamza96@gmail.com

Keywords

Paraneoplastic pemphigus, radiotherapy, nasopharyngeal carcinoma

Abstract

Paraneoplastic pemphigus arising in association with non-haematological cancers is extremely rare, and there are no reported cases of a patient developing this in the setting of nasopharyngeal carcinoma and only 2 reported cases of patients developing this in response to radiotherapy. Here, we present the case of a patient who developed radiotherapy-associated paraneoplastic pemphigus in the setting of nasopharyngeal carcinoma and who then developed multiple complications.

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References

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  2. Anhalt GJ, Kim SC, Stanley JR, Korman NJ, Jabs DA, Kory M, et al. Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia. N Engl J Med 1990;323(25):1729–1735.
  3. Mimouni D, Anhalt GJ, Lazarova Z, Aho S, Kazerounian S, Kouba DJ, et al. Paraneoplastic pemphigus in children and adolescents. Br J Dermatol 2002;147(4):725–732.
  4. Fried R, Lynfield Y, Vitale P, Anhalt G. Paraneoplastic pemphigus appearing as bullous pemphigoid-like eruption after palliative radiation therapy. J Am Acad Dermatol 1993;29(5 Pt 2):815–817.
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Published

2020-11-12

Issue

Vol. 7 No. 12 (2020)

How to Cite

1.
Khair AH, Dar AA, Sheikh AB, Malik AI. Radiotherapy-Associated Paraneoplastic Pemphigus and Its Complications in a Patient with Nasopharyngeal Carcinoma. EJCRIM [Internet]. 2020 Nov. 12 [cited 2026 Nov. 3];7(12). Available from: https://ejcrim.com/index.php/ejcrim/article/view/2026

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