DOI: 10.12890/2015_000196

Seizure and Profound Hypokalemia: Unusual Presentation of Primary Hyperparathyroidism

Authors

  • Yasuto Nakasone Diabetes Center, Aizawa Hospital, Matsumoto
  • Shinya Uchino Noguchi Thyroid Clinic and Hospital Foundation, Beppu
  • Yuka Sato Diabetes Center, Aizawa Hospital, Matsumoto
  • Keishi Yamauchi Diabetes Center, Aizawa Hospital, Matsumoto
  • Toru Aizawa Diabetes Center, Aizawa Hospital, Matsumoto

taizawax@ai-hosp.or.jp

Keywords

Seizure, hypokalaemia, hyperparathyroidism, itraconazole

Abstract

Abstract:

A 68-year-old man was admitted because of tonic–clonic convulsion. He had been receiving 200 mg itraconazole for 10 days. He had hypokalaemia (2.2 mEq/l), hypercalcaemia (Cacorr 11.0 mg/dl) and elevated serum parathyroid hormone (PTH, 95 pg/ml). Ultrasound examination of the neck revealed a low echoic tumour. Cessation of itraconazole and fluid supplementation eradicated clinical symptoms and profound hypokalaemia, but serum potassium remained low normal (3.4 mEq/l) and the mild hypercalcaemia and elevated PTH were unchanged. To conclude, a small amount of itraconazole (200 mg) precipitated profound hypokalaemia and seizure in a patient with mild hyperparathyroidism and low normal serum potassium.

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References

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Published

2015-06-30

Issue

Vol. 2 No. 3 (2015)

How to Cite

1.
Nakasone Y, Uchino S, Sato Y, Yamauchi K, Aizawa T. Seizure and Profound Hypokalemia: Unusual Presentation of Primary Hyperparathyroidism. EJCRIM [Internet]. 2015 Jun. 30 [cited 2026 Nov. 3];2(3). Available from: https://ejcrim.com/index.php/ejcrim/article/view/196

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