DOI: 10.12890/2015_000189

Psychiatric Manifestations of Sporadic Creutzfeldt-Jakob Disease Simulate Depressive Disorder with Psychotic Symptoms

Authors

  • Joana Almeida Espírito Santo Internal Medicine Department, University Hospital Center of Coimbra, Coimbra
  • Rui Garcia Internal Medicine Department, University Hospital Center of Coimbra, Coimbra
  • Rui Marques dos Santos Internal Medicine Department, University Hospital Center of Coimbra, Coimbra
  • João Lemos Neurology Department, University Hospital Center of Coimbra, Coimbra
  • Isabel Santana Neurology Department, University Hospital Center of Coimbra, Coimbra

joana_espiritosanto@hotmail.com

Abstract

Creutzfeldt–Jakob disease (CJD) is a rare and fatal neurodegenerative disorder with a broad spectrum of early clinical manifestations, comprising neurological and psychiatric symptoms. The authors report the case of a patient admitted with a diagnosis of depressive disorder with psychotic symptoms, with post-mortem confirmation of CJD and discuss how CJD’s clinical heterogeneity can lead to misdiagnosis of the disease. Despite CJD’s unique pathogenesis, its kaleidoscopic presentation justifies the integrated investigation of patients with psychiatric symptoms, avoiding restrictive diagnosis.

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References

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Published

2015-03-10

Issue

Vol. 2 No. 1 (2015)

How to Cite

1.
Espírito Santo JA, Garcia R, Marques dos Santos R, Lemos J, Santana I. Psychiatric Manifestations of Sporadic Creutzfeldt-Jakob Disease Simulate Depressive Disorder with Psychotic Symptoms. EJCRIM [Internet]. 2015 Mar. 10 [cited 2026 Nov. 3];2(1). Available from: https://ejcrim.com/index.php/ejcrim/article/view/189

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