DOI: 10.12890/2015_000172

Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report

Authors

  • Chris Anthony Department of Cardiology, St Vincent’s Hospital, Sydney
  • Meenal Sharma Department of Cardiology, St Vincent’s Hospital, Sydney
  • Roberto Spina Department of Cardiology, St Vincent’s Hospital, Sydney
  • Peter S Macdonald Department of Cardiology, St Vincent’s Hospital, Sydney
  • Jacob Sevastos Department of Nephrology, St Vincent’s Hospital, Sydney

chris007_7@hotmail.com

Abstract

Introduction: Despite adherence to current guidelines regarding dose adjustment and drug-level monitoring, beta-lactam-induced encephalopathy can still occur in the setting of chronic renal impairment.

Case Report: We report what we believe is the first case of piperacillin- and tazobactam-induced encephalopathy in a patient with pre-existing cefepime-induced encephalopathy in the context of end-stage kidney disease despite adequate dose adjustment for renal impairment.

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References

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Published

2015-02-11

Issue

Vol. 2 No. 1 (2015)

How to Cite

1.
Anthony C, Sharma M, Spina R, Macdonald PS, Sevastos J. Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report. EJCRIM [Internet]. 2015 Feb. 11 [cited 2026 Nov. 3];2(1). Available from: https://ejcrim.com/index.php/ejcrim/article/view/172

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