DOI: 10.12890/2014_000156

Non-Celiac Gluten Sensitivity and Autoimmunity. A Case Report.

Authors

  • Carlos Isasi Department of Rheumatology, Hospital Puerta de Hierro Majadahonda, Madrid
  • Isabel Colmenero Histopathology Department, Birmingham Children's Hospital, Birmingham
  • Fernando Casco Department of Pathology, Histiocitomed, Madrid
  • Eva Tejerina Department of Pathology, Hospital Puerta de Hierro Majadahonda, Madrid
  • Natalia Fernandez-Puga Department of Gastroenterology, Hospital Puerta de Hierro Majadahonda, Madrid

carlos.isasi@gmail.com

Keywords

Coeliac disease, gluten sensitivity, autoimmunity

Abstract

Introduction, objective: To present a case report in which the finding of non-coeliac gluten sensitivity was decisive for the treatment of a complex autoimmune disease.
Materials and methods: A 43-year-old woman with polyarthritis, psoriatic features, anti-SSA/Ro and anti-cyclic citrullinated peptide antibodies, with refractory course, was evaluated for gluten sensitivity despite negative serology for coeliac disease.
Results: The patient carried the HLA DQ2 haplotype and duodenal biopsy showed lymphocytic enteritis. A gluten-free diet resolved the clinical picture and permitted tapering of immunosuppressive therapy.
Conclusion: Non-coeliac gluten sensitivity can be associated with autoimmunity despite the absence of the specific autoantibodies of coeliac disease.

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References

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Published

2014-12-05

Issue

Vol. 1 No. 1 (2014)

How to Cite

1.
Isasi C, Colmenero I, Casco F, Tejerina E, Fernandez-Puga N. Non-Celiac Gluten Sensitivity and Autoimmunity. A Case Report. EJCRIM [Internet]. 2014 Dec. 5 [cited 2026 Nov. 4];1(1). Available from: https://ejcrim.com/index.php/ejcrim/article/view/156