DOI: 10.12890/2014_000146

Paraneoplastic Polymyalgia Rheumatica as Manifestation of a Pancreatic Neuroendocrine Tumour

Authors

  • Luís Felipe Linhares Santos Department of Internal Medicine, Coimbra University Hospital, Coimbra
  • Cláudia Susana Teixeira Graça Fernandes Department of Infectious Diseases, Coimbra University Hospital, Coimbra
  • António Pedro Mendes Duarte Rodrigues Teotónio Department of Internal Medicine, Coimbra University Hospital, Coimbra

lscasa@sapo.pt

Keywords

Paraneoplastic syndrome, polymyalgia rheumatica, cancer

Abstract

Autoimmune diseases may present as paraneoplastic syndrome. This is especially recognized in the case of polymyositis/dermatomyositis, but is less common in polymyalgia rheumatica. The authors describe the case of a 73-year-old man who presented with pain and stiffness of the scapular and pelvic girdles associated with asthenia lasting for a few weeks. The presence of therapeutic resistance and other atypical features directed the investigation towards the search of an occult malignancy. Patient evaluation revealed a pancreatic neuroendocrine tumour. After surgical treatment of the underlying neoplasia, the patient recovered fully with resolution of the rheumatic disease.

View the entire article

Downloads

References

  1. Fam AG. Paraneoplastic rheumatic syndrome, Baillieres Best Pract Res Clin Rheumatol 2000;14:515–533.
  2. Milan SA, Yeo CJ. Neuroendocrine tumors of the pancreas, Curr Opin Oncol 2012;24:46–55.
  3. Dasgupta B, Cimmino M, Kremers H, Schmidt W, Schirmer M, Salvarani C et al. 2012 Provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative, Arthritis Rheum 2012;64:943–954.
  4. Cocquempot K, Defuentes G, Duron-Martineau S, Berets O, Vaylet F, Margery J. Polymyalgia rheumatica revealing a lung cancer, Rev Mal Respir 2013;30:67–70.
  5. Kehler T, Curković B. Polymyalgia rheumatica and colon malignancy: case report. Clin Rheumatol 2006;25:764–765.
  6. Kaltsas G, Androulakis II, Herder WW, Grossman AB. Paraneoplastic syndromes secondary to neuroendocrine tumours, Endocr Relat Cancer 2010;17:R173–R193.

Published

2014-11-21

How to Cite

1.
Linhares Santos LF, Teixeira Graça Fernandes CS, Mendes Duarte Rodrigues Teotónio AP. Paraneoplastic Polymyalgia Rheumatica as Manifestation of a Pancreatic Neuroendocrine Tumour. EJCRIM [Internet]. 2014 Nov. 21 [cited 2026 Nov. 3];1(1). Available from: https://ejcrim.com/index.php/ejcrim/article/view/146