DOI: 10.12890/2019_001247

Terlipressin-related Ischaemic Necrosis of the Skin: A Rare Complication

Authors

  • Sara Simões Macedo Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal
  • Cátia Cabral Department of Internal Medicine, Hospital Trofa Saúde Vila Real, Vila Real, Portugal
  • António Novais Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal
  • Mónica Teixeira Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal
  • Anna Knock Department of Internal Medicine, Hospital de Braga, Braga, Portugal

macedo_sara@hotmail.com

Keywords

Terlipressin, vasoconstrictor agents, skin necrosis, hepatorenal syndrome, liver cirrhosis

Abstract

Terlipressin is used for the treatment of bleeding oesophageal varices and hepatorenal syndrome in patients with cirrhosis. Adverse effects are usually minimal. However, potentially serious side effects such as skin necrosis involving the extremities, scrotum, trunk and abdominal skin can rarely occur. Our patient had greater skin involvement than other described cases. We present the case of a patient with extensive skin necrosis, unrelated to the infusion site, in the lower and upper limbs, scrotum and abdomen after the use of terlipressin. Skin necrosis secondary to terlipressin is a rare complication and early identification is essential so the drug can be immediately suspended.

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Published

2019-10-18

Issue

Vol. 6 No. 11 (2019)

How to Cite

1.
Macedo SS, Cabral C, Novais A, Teixeira M, Knock A. Terlipressin-related Ischaemic Necrosis of the Skin: A Rare Complication. EJCRIM [Internet]. 2019 Oct. 18 [cited 2026 Nov. 3];6(11). Available from: https://ejcrim.com/index.php/ejcrim/article/view/1247

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