DOI: 10.12890/2019_001218

Hypercalcemia and Extensive Chest Metastasis of Vulvar Squamous Cell Carcinoma

Authors

  • Ernestina Natália Mota Serviço de Medicina 2, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Isabel Paulos Mesquita Serviço de Medicina 2, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Carlos Pires Serviço de Medicina 2, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Rui M.M. Victorino Serviço de Medicina, Hospital Santa Maria, Faculdade de Medicina de Lisboa, Centro Hospitalar Lisbona Norte, Lisbon, Portugal

emota83@gmail.com

Keywords

Squamous cell carcinoma of the vulva, paraneoplastic hypercalcemia, pulmonary metastasis of vulvar squamous cell carcinoma

Abstract

A 73-year-old woman with a diagnosis of vulvar carcinoma submitted to curative surgery 5 years previously, presented to the emergency department with prostration and vulvar haemorrhage. Although the gynaecological examination was unremarkable, she had a mass in the left chest wall and hypercalcemia. A CT scan of the thorax revealed a voluminous left hemithorax mass invading the mediastinum, lung, pleura and chest wall. Ultrasound-guided biopsy of the mass showed infiltration by a well-differentiated keratinizing squamous cell carcinoma (SCC). This case report describes an extremely rare metastatic pattern in vulvar SCC concomitant with paraneoplastic hypercalcemia.

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Published

2019-09-02

How to Cite

1.
Mota EN, Mesquita IP, Pires C, Victorino RM. Hypercalcemia and Extensive Chest Metastasis of Vulvar Squamous Cell Carcinoma. EJCRIM [Internet]. 2019 Sep. 2 [cited 2026 Nov. 4];6(9). Available from: https://ejcrim.com/index.php/ejcrim/article/view/1218