DOI: 10.12890/2019_001066

Acute Colchicine-induced Neuromyopathy in a Patient Treated with Atorvastatin and Clarithromycin

Authors

  • José M. Olmos-Martínez Gastroenterology and Hepatology Department, Hospital Universitario Marqués de Valdecilla-IDIVAL, Universidad de Cantabria, Santander, Spain
  • Helena Molina Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla-IDIVAL, Universidad de Cantabria, Santander, Spain
  • Cristina Salas Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla-IDIVAL, Universidad de Cantabria, Santander, Spain
  • José M. Olmos Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla-IDIVAL, Universidad de Cantabria, Santander, Spain
  • José L. Hernández Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla-IDIVAL, Universidad de Cantabria, Santander, Spain

jmolmos89@gmail.com

Keywords

Colchicine, neuromyopathy, atorvastatin, clarithromycin

Abstract

Neuromyopathy is a rare side effect of chronic colchicine therapy, especially without renal impairment. Drugs interacting with colchicine metabolism through CYP3A4 can accelerate accumulation and toxicity. We describe a case of an interaction between atorvastatin, clarithromycin and colchicine resulting in acute neuromyopathy.

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Published

2019-03-18

Issue

Vol. 6 No. 3 (2019)

How to Cite

1.
Olmos-Martínez JM, Molina H, Salas C, Olmos JM, Hernández JL. Acute Colchicine-induced Neuromyopathy in a Patient Treated with Atorvastatin and Clarithromycin. EJCRIM [Internet]. 2019 Mar. 18 [cited 2026 Nov. 3];6(3). Available from: https://ejcrim.com/index.php/ejcrim/article/view/1066

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