Primary Hepatic Diffuse Large B-cell Lymphoma Mimicking Acute Fulminant Hepatitis

A Case Report and Review of the Literature

  • Toni El Murr Department of Internal Medicine, Middle East Institute of Health, Faculty of Medical Science, Lebanese University, Hadath, Lebanon
  • Ricardo El Nouwar Department of Internal Medicine, Middle East Institute of Health, Faculty of Medical Science, Lebanese University, Hadath, Lebanon

Keywords

Primary hepatic lymphoma, non-Hodgkin’s lymphoma, diffuse large B-cell lymphoma, cute fulminant hepatitis

Abstract

Primary hepatic lymphoma (PHL) is a rare variant of non-Hodgkin's lymphoma. Diffuse hepatic involvement is uncommon and therefore presentation as progressive hepatitis or acute fulminant hepatic failure is rare. Acute onset of signs and symptoms can mimic a variety of infectious and inflammatory disorders, thus delaying the diagnosis. A high index of suspicion and liver biopsy early in the course of liver dysfunction may establish the diagnosis and allow rapid initiation of chemotherapy to prevent a fatal outcome. In this report, we describe a rare case of fulminant primary hepatic diffuse large B-cell lymphoma in a 55-year-old woman who died 2 weeks after admission, before the initiation of chemotherapy.

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  • Published: 2018-04-19

    Issue: Vol 5 No 6 (view)

    Section: Articles

    How to cite:
    El Murr, T., & El Nouwar, R. (2018). Primary Hepatic Diffuse Large B-cell Lymphoma Mimicking Acute Fulminant Hepatitis. European Journal of Case Reports in Internal Medicine, 5(6). https://doi.org/https://doi.org/10.12890/2018_000878