A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome

  • Takahiro Miyakoshi Diabetes Center, Department of Neurology, Aizawa Hospital, Matsumoto
  • Mamoru Satoh Division of Clinical Mass Spectrometry, Chiba University Hospital, Chiba
  • Fumio Nomura Division of Clinical Mass Spectrometry, Chiba University Hospital, Chiba
  • Takao Hashimoto Department of Neurology, Aizawa Hospital, Matsumoto
  • Toru Aizawa Diabetes Center, Department of Neurology, Aizawa Hospital, Matsumoto
Keywords: Hikikomori syndrome, Hypocalcemia, Hypovitaminosis D

Abstract

Objective: To describe hypocalcaemia due to vitamin D deficiency in ‘hikikomori’ syndrome.
Materials and methods: A 37-year-old man with ‘hikikomori’ syndrome for a year was admitted with hypocalcaemia (serum ionic calcium 1.17 mmol/l). Serum 1,25(OH)2-vitamin D3 determined by liquid chromatography–tandem mass spectrometry was depressed at 12.1 pg/ml (29.0 pmol/l) and plasma intact PTH elevated at 324 ng/l. Administration of 1 μg/day 1α(OH)-vitamin D3 and 1 g/day calcium lactate for 1 week normalized calcium and PTH, and raised 1,25(OH)2-vitamin D3 to low normal levels.
Conclusion: This is the first report of hypocalcaemia due to vitamin D deficiency in a patient with ‘hikikomori’ syndrome.

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  • Published: 2017-09-28

    Issue: Vol 4 No 7 (view)

    Section: Articles

    How to cite:
    Miyakoshi, T., Satoh, M., Nomura, F., Hashimoto, T., & Aizawa, T. (2017). A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome. European Journal of Case Reports in Internal Medicine, 4(7). https://doi.org/https://doi.org/10.12890/2017_000634