Light-Chain Deposition Disease with Prominent Hepatic Involvement

  • Ana Vaz Cristino Serviço de Medicina Interna, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real
  • Carmen Tavares Pais Serviço de Medicina Interna, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real
  • Renata Violante Silva Serviço de Medicina Interna, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real
  • Paulo Carrola Serviço de Medicina Interna, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real
Keywords: Light-chain deposition, monoclonal, plasma cell

Abstract

Light-chain deposition disease (LCDD) is a rare monoclonal gammopathy that involves the deposition of light chains (LC) in multiple organs, leading to progressive dysfunction. The kidney is usually the most affected organ and responsible for the initial clinical manifestations. We present the case of a patient with LCDD with prominent liver involvement (marked cholestasis, hepatomegaly and portal hypertension) but with no evidence of coexisting lymphoproliferative disorder.

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  • Published: 2017-04-27

    Issue: Vol 4 No 3 (view)

    Section: Articles

    How to cite:
    Cristino, A., Pais, C., Silva, R., & Carrola, P. (2017). Light-Chain Deposition Disease with Prominent Hepatic Involvement. European Journal of Case Reports in Internal Medicine, 4(3). https://doi.org/https://doi.org/10.12890/2017_000545