Kaposi’s Sarcoma Presenting as Lymphadenopathy in an Immunocompetent Patient
  • Hana Zoubeidi
    Department of Internal Medicine, Habib Thameur Hospital, Tunis, Tunisia
  • Zohra Aydi
    Department of Internal Medicine, Habib Thameur Hospital, Tunis, Tunisia
  • Fatma Daoud
    Department of Internal Medicine, Habib Thameur Hospital, Tunis, Tunisia
  • Imen Rachdi
    Department of Internal Medicine, Habib Thameur Hospital, Tunis, Tunisia
  • Wafa Koubaa
    Anatomopatholgy department, Habib Thameur Hospital, Tunis, Tunisia
  • Raja Jouini
    Anatomopathology Department, Habib Thameur Hospital, Tunis, Tunisia
  • Lilia Baili
    Department of Internal Medicine, Habib Thameur Hospital, Tunis, Tunisia
  • Achraf Debbiche
    Anatomopathology department, Habib Thameur Hospital, Tunis, Tunisia
  • Besma Ben Dhaou
    Department of Internal Medicine, Habib Thameur Hospital, Tunis, Tunisia
  • Fatma Boussema
    Department of Internal Medicine, Habib Thameur Hospital, Tunis, Tunisia

Keywords

Kaposi’s sarcoma (KS), lymphadenopathy, Human Herpes Virus 8 (HHV-8).

Abstract

Introduction: Kaposi’s sarcoma (KS) is an angioproliferative disorder first described in 1872 by Moritz Kaposi. Four main clinical presentations of KS have been described: classic, endemic, iatrogenic and epidemic. KS involvement of the lymph nodes is extremely uncommon in the classical variant form, especially if it precedes the skin manifestations. We describe the case of an elderly HIV-negative patient presenting with lymphadenopathy who was found to have KS.
Case Report: A 67-year-old patient was admitted for exploration of polyadenopathies in the context of a general decline in health. Physical examination revealed an erythematosus left lower limb rash associated with angiomatous nodules and multiple lymphadenopathies. The diagnosis of erysipelas in the left leg was retained and the patient was treated with good evolution of the rash but persistence of the angiomatous nodules and the polyadenopathies. Skin and lymph node biopsies led to a diagnosis of KS. The patient is proposed for polychemotherapy.
Conclusion: KS must be suspected in lymphadenopathies despite the absence of typical cutaneous signs of the disease and in immunocompetent patients.

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    Published: 2016-11-28
    Issue: Vol. 3 No. 7 (view)

    How to cite:
    1.
    Zoubeidi H, Aydi Z, Daoud F, Rachdi I, Koubaa W, Jouini R, Baili L, Debbiche A, Ben Dhaou B, Boussema F. Kaposi’s Sarcoma Presenting as Lymphadenopathy in an Immunocompetent Patient. EJCRIM 2016;3 doi:10.12890/2016_000493.