Ventricular Fibrillation in Patient with Multi-vessel Coronary Spasm Four Days after the Initiation of Oral Beta-blocker
  • Manabu Kurabayashi
    Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City
  • Hidetoshi Suzuki
    Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City
  • Tsukasa Shimura
    Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City
  • Yasuteru Yamauchi
    Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City
  • Kaoru Okishige
    Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City

Keywords

Coronary spasm, ventricular fibrillation, beta-blocker, acetylcholine provocation test.

Abstract

We describe a case of ventricular fibrillation occurring in a patient with multi-vessel coronary spasm after the initiation of an oral beta-blocker. A 56-year-old man began to experience chest discomfort and his computed tomography revealed intermediate coronary stenoses. He was administered medications including an oral beta-blocker but suddenly collapsed while walking 4 days later. An automated external defibrillator detected ventricular fibrillation and delivered successful electrical cardioversion. An acetylcholine provocation test after stabilization of the status revealed triple-vessel coronary spasm. Beta-blockers may provoke exacerbation of coronary spasm and result in lethal arrhythmia.

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    Published: 2016-07-27
    Issue: Vol. 3 No. 5 (view)


    How to cite:
    1.
    Kurabayashi M, Suzuki H, Shimura T, Yamauchi Y, Okishige K. Ventricular Fibrillation in Patient with Multi-vessel Coronary Spasm Four Days after the Initiation of Oral Beta-blocker. EJCRIM 2016;3 doi:10.12890/2016_000439.