Intravascular Lymphoma as an Uncommon Cause of Anasarca

  • Eleni Mylona Fifth Department of Medicine, Evangelismos General Hospital, Athens
  • Styliani Golfinopoulou Fifth Department of Medicine, Evangelismos General Hospital, Athens
  • Pelagia Sfakianaki Fifth Department of Medicine, Evangelismos General Hospital, Athens
  • George Kyriakopoulos Pathology Department, Evangelismos General Hospital, Athens
  • Ioannis Tsonis Ematology Department, Evangelismos General Hospital, Athens
  • Theofanis Apostolou Nephrology Department, Evangelismos General Hospital, Athens
  • Christina Vourlakou Pathology Department, Evangelismos General Hospital, Athens
  • Athanasios Skoutelis Evangelismos General Hospital

Keywords

Anasarca edema, hemophagocytosis, Intravascular lymphoma.

Abstract

Objectives: To report a case of intravascular lymphoma (IVL) in a Caucasian patient who presented with anasarca as his sole clinical sign.

Material and Methods: A man presented with anasarca-type oedema and fatigue. After excluding heart failure, hepatic cirrhosis, nephrotic syndrome, hypothyroidism, AL-amyloidosis and adverse drug reaction which can all cause oedema, we turned our attention to capillary permeability disorders.

Results: Closer review of the bone marrow aspirate demonstrated haemophagocytic histiocytosis, while core, renal and duodenal biopsies showed a B-cell IVL.

Conclusion: The differential diagnosis of anasarca, a relatively common clinical sign, should include IVL although the diagnosis may still be challenging.

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  • Published: 2016-07-27

    Issue: Vol. 3 No. 5 (view)

    Section: Articles

    How to cite:
    1.
    Mylona E, Golfinopoulou S, Sfakianaki P, Kyriakopoulos G, Tsonis I, Apostolou T, Vourlakou C, Skoutelis A. Intravascular Lymphoma as an Uncommon Cause of Anasarca. EJCRIM 2016;3 doi:10.12890/2016_000424.