Can This Be Considered Fondaparinux-induced Thrombocytopenia?
  • Barbara Mariotti
    Internal Medicine Department, Azienda Ospedaliero-Universitaria S.Maria della Misericordia, Udine, Italy
  • Paolo Rossi
    Internal Medicine Department, Azienda Ospedaliero-Universitaria S.Maria della Misericordia, Udine, Italy
  • Enrico Barboni
    Internal Medicine Department, Azienda Ospedaliero-Universitaria S.Maria della Misericordia, Udine, Italy

Abstract

We present a case of an old woman with previously documented heparin-induced thrombocytopenia (HIT),treated with fondaparinux, who presented with thrombocytopenia and venous thrombosis after exposure to a preventive dose of fondaparinux duringorthopaedic surgery.
Any accidental exposure to heparin was avoided. Other causes of thrombocytopenia were excluded andantigenic tests combined with clinical probability made a diagnosis of HIT likely.
Can this be considered a possible case of fondaparinux-related HIT, despite the intense and earlydecrease in platelets, as usually happens in rapid-onset HIT, and the fact that previous exposure to fondaparinux had occurred 5 months previously?

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References

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    Published: 2014-04-16
    Issue: Vol. 1 (2014) (view)

    How to cite:
    1.
    Mariotti B, Rossi P, Barboni E. Can This Be Considered Fondaparinux-induced Thrombocytopenia?. EJCRIM 2014;1 doi:10.12890/2014_000042.