Acute Acalculous Cholecystitis as a Presenting Manifestation in Systemic Lupus Erythematosus
  • Sonmoon Mohapatra
    Department of Internal Medicine, Rutgers Robert Wood Johnson Medical School/Saint Peter's University Hospital
  • Debra R Goldstein
    Department of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School/Saint Peter's University Hospital
  • Akshat Kumar
    Department of Internal Medicine, Rutgers Robert Wood Johnson Medical School/Saint Peter's University Hospital
  • Trisha Saha
    Department of Internal Medicine, Rutgers Robert Wood Johnson Medical School/Saint Peter's University Hospital
  • Damodar Penigalapati
    Department of Internal Medicine, Rutgers Robert Wood Johnson Medical School/Saint Peter's University Hospital

Keywords

Systemic lupus erythematosus, Acalculous cholecystitis, Gallbladder vasculitis

Abstract

Systemic lupus erythematosus (SLE) is known to involve the gastrointestinal tract, but gallbladder involvement is rare. The authors report the case of a 26-year-old postpartum female who presented with acute right upper quadrant abdominal pain and was diagnosed with acute acalculous cholecystitis (AAC). In the presence of concomitant features of nephritis, pericardial effusion, anaemia and positive ANA titre, the diagnosis of SLE was confirmed during hospitalisation. Histopathological analysis of the gall bladder revealed evidence of vasculitis. Although rare, AAC can be the first presentation of patients diagnosed with SLE. Prompt diagnosis and management results in a better patient outcome. 

VIEW THE ENTIRE ARTICLE

References

  • Manuel V, Pedro GM, Cordeiro LB, Miranda SM. Acute acalculous cholecystitis in systemic lupus erythematosus: a rare initial manifestation. Rev Bras Reumatol (English Edition) 2014. DOI:10.1016/j.rbre.2014.03.027.
  • Yun Jung Choi HYY, Seol A Jang, Myong Joo Hong, Won Seok Lee, Wan-Hee Yoo. A case of systemic lupus erythematosus initially presented with acute acalculous cholecystitis. J Rheum Dis 2014;21:140–142.
  • Hegarty J, Chiu DY, Middleton RJ, Haeney MM, Newstead CG, Bruce IN, et al. Systemic lupus erythematosus, eosinophilic vasculitis and acalculous cholecystitis. Nephrol Dial Transplant 2006;21:792–795.
  • Montini KM, Tulchinsky M. Applied hepatobiliary scintigraphy in acute cholecystitis. Appl Radiol 2015;44:22–30.
  • Owen CC, Jain R. Acute acalculous cholecystitis. Curr Treat Options Gastroenterol 2005;8:99–104.
  • Views: 1977
    HTML downloads: 1675
    PDF downloads: 583


    Published: 2016-06-07
    Issue: Vol. 3 No. 4 (view)


    How to cite:
    1.
    Mohapatra S, Goldstein DR, Kumar A, Saha T, Penigalapati D. Acute Acalculous Cholecystitis as a Presenting Manifestation in Systemic Lupus Erythematosus. EJCRIM 2016;3 doi:10.12890/2016_000408.