Aortitis Secondary to Cogan’s Syndrome: A Rare Cause of Fever of Unknown Origin


Aortitis, Cogan’s syndrome, fever of unknown origin


Fever of unknown origin remains a diagnostic challenge. Aortitis, defined as inflammation of the aorta, has multiple infectious and non-infectious causes.<br/>
We report the case of an elderly woman with vertigo and bilateral hearing loss, presenting with fever of unknown origin. Blood tests were remarkable for leucocytosis with neutrophilia, elevation of C-reactive protein and the erythrocyte sedimentation rate, and positive antinuclear antibodies and rheumatoid factor, and an unremarkable search for multiple infectious causes of fever. During admission the patient developed a bilateral red eye. Abdominal and chest computed tomography was performed and demonstrated signs of aortitis.
Due to the coexistence of aortitis, ocular inflammation, vertigo and bilateral hearing loss in a patient with persistent fever and elevation of inflammatory parameters, a presumptive diagnosis of Cogan’s syndrome was made, with improvement after initiation of steroid therapy.



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    Published: 2022-10-05
    Issue: 2022: Vol 9 No 10 (view)

    How to cite:
    Rosado MM, Queirós C, Conceição V, Vieira NB, Arez L. Aortitis Secondary to Cogan’s Syndrome: A Rare Cause of Fever of Unknown Origin. EJCRIM 2022;9 doi:10.12890/2022_003585.