Overlapping Presentations of HELLP Syndrome and COVID-19: A Case Report
  • Leila C Tou
    Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA
  • Andrew A Wang
    Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA
  • Taha A Siddiqui
    Philadelphia College of Osteopathic Medicine, NW, Suwanee, USA
  • Michael Mamone
    Department of Internal Medicine, Florida Atlantic University, Boca Raton, FL, USA


COVID-19, SARS-CoV-2, preeclampsia, HELLP, gestational hypertension


Introduction: Hemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome is a leading cause of maternal mortality. The emergence of Coronavirus disease 2019 (COVID-19) has led to challenges in diagnosing HELLP syndrome due to overlapping clinical and laboratory presentations. We report a case of HELLP syndrome complicated by COVID-19 infection.

Case Description: An otherwise healthy pregnant 31-year-old female presented with fever, myalgia, and headache. She was found to be COVID-positive with laboratory signs of HELLP syndrome. Symptoms and laboratory findings trended toward normal post-partum confirming the diagnosis of HELLP syndrome.

Discussion: A prompt diagnosis of HELLP syndrome is essential to avoid maternal and fetal complications. Clinicians should be aware of the similarities in presentation between HELLP syndrome and COVID-19 for timely diagnosis and treatment.



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    Published: 2022-09-07
    Issue: 2022: Vol 9 No 9 (view)

    How to cite:
    Tou L, Wang A, Siddiqui T, Mamone M. Overlapping Presentations of HELLP Syndrome and COVID-19: A Case Report. EJCRIM 2022;9 doi:10.12890/2022_003540.