A Transient Inflammatory Reaction with a B-Cell Lymphoid Infiltrate and Dysplastic Bone Marrow Changes Associated with the BNT162b2 COVID-19 Vaccine
  • Daniella Vronsky
    Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel
  • Shimrit Hershkowitz
    Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel
  • Alon Hershko
    Department of Medicine, Hadassah University Hospital, Jerusalem, Israel; Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel
  • Noa Eliakim-Raz
    Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Keywords

SARS-CoV-2, COVID-19 vaccine, lymphoma-like reaction

Abstract

COVID-19 vaccines were introduced soon after the COVID-19 pandemic emerged in 2020. Various side effects were reported worldwide, including several types of common systemic side effects such as fever and general fatigue. Reports of other rare manifestations also emerged. We report the case of an adult male with a rare systemic syndrome mimicking lymphoma after he had received the first dose of an mRNA-based COVID-19 vaccine. After nearly 6 months of investigation with suspicion for an infection or malignancy, all symptoms resolved, laboratory tests normalized, and imaging showed no sign of active disease.

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    Published: 2022-06-27
    Issue: 2022: Vol 9 No 6 (view)

    How to cite:
    1.
    Vronsky D, Hershkowitz S, Hershko A, Eliakim-Raz N. A Transient Inflammatory Reaction with a B-Cell Lymphoid Infiltrate and Dysplastic Bone Marrow Changes Associated with the BNT162b2 COVID-19 Vaccine. EJCRIM 2022;9 doi:10.12890/2022_003381.